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We design new strategies against infections and Antimicrobial Resistance
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lucaferrari
A phage-inspired therapy against infections
Bacteriophage-derived endolysins, enzymes that target and degrade the bacterial cell wall by hydrolyzing the peptidoglycan layer are leading candidate for treating multidrug-resistant (MDR) bacteria.
Read moreOur research
Our Infection Dynamics Unit proposes a research vision that aims to revolutionize the way we treat infections caused by intracellular pathogens, with the aim of finding a universal therapy for...
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Infection and Cell Senescence
Cellular senescence impairs immune responses promoting chronic inflammation, and pathogen survival. Our research explores how infection-induced senescence can be exploited for new antimicrobial therapeutic strategies.
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News & Updates
We will routinely post lab updates. It can be an opening, a new publication, or a fancy picture of the month. Stay tuned! Latest News
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Join our team! We are always pleased to consider expressions of interest from prospective postdocs, PhD students, and Master’s students. Additionally, we welcome researchers who are interested in applying for...
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Immune Evasion
Mycobacteria are able to evade and hijack immune defenses persisting within macrophages and leading to chronic infections. Our research aims to identify new strategies to enhance pathogen clearance and improve...
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Cell-derived nanoparticles
Cell-derived nanoparticles include a diverse array of nanoscale structures originating from various cell types (cell ghosts, exosomes, lipid-based and peptidic nanoparticles), each exhibiting unique properties.
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Extracellular Matrix of Infected Cells
We investigate how infections alter the extracellular matrix (ECM). Focusing on lung infections caused by mycobacteria and conditions like tissue fibrosis, we integrate tissue engineering, biomaterials, and infection dynamics to...
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The Facilities
We are equipped with the highest standards for performing infection experiments under safe conditions. Our Biosafety Level-3 (BSL3) bio-containament facilities are a gold standard worldwide. We have the latest confocal...
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