We design new strategies against infections and Antimicrobial Resistance
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lucaferrari
Bacteriophage-derived endolysins, enzymes that target and degrade the bacterial cell wall by hydrolyzing the peptidoglycan layer are leading candidate for treating multidrug-resistant (MDR) bacteria.
Read moreOur Infection Dynamics Unit proposes a research vision that aims to revolutionize the way we treat infections caused by intracellular pathogens, with the aim of finding a universal therapy for...
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Cellular senescence impairs immune responses promoting chronic inflammation, and pathogen survival. Our research explores how infection-induced senescence can be exploited for new antimicrobial therapeutic strategies.
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We will routinely post lab updates. It can be an opening, a new publication, or a fancy picture of the month. Stay tuned! Latest News
Read moreJoin our team! Postdoc opening We are seeking a Postdoctoral Researcher to investigate how cellular senescence is induced during infection and how this state contributes to chronic bacterial persistence. Our...
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Mycobacteria are able to evade and hijack immune defenses persisting within macrophages and leading to chronic infections. Our research aims to identify new strategies to enhance pathogen clearance and improve...
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Cell-derived nanoparticles include a diverse array of nanoscale structures originating from various cell types (cell ghosts, exosomes, lipid-based and peptidic nanoparticles), each exhibiting unique properties.
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We investigate how infections alter the extracellular matrix (ECM). Focusing on lung infections caused by mycobacteria and conditions like tissue fibrosis, we integrate tissue engineering, biomaterials, and infection dynamics to...
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We are equipped with the highest standards for performing infection experiments under safe conditions. Our Biosafety Level-3 (BSL3) bio-containament facilities are a gold standard worldwide. We have the latest confocal...
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