We are pleased to announce that our latest review on the regulation of monocyte differentiation into distinct macrophage phenotypes has been published in Frontiers in Immunology!
The article provides an overview of the processes leading to the generation of M0, M1, M2, and tissue-resident–like macrophages, along with their phenotypic characterization. It further discusses the metabolic programs, secretion of pro- and anti-inflammatory mediators, and functional properties associated with these cell types. Finally, the review offers a critical assessment of the use of monocyte-derived macrophages (MDMs), highlighting both their advantages and limitations.
If this topic is of interest, we invite you to read the full article by clicking here.
